Swedish Medical Center Cherry Hill Family Medicine Residency

In 1866, Russian scientist Alexander Saytzeff isolated a nearly curious and peculiar chemical compound. It was crystalline, odour-less, non-toxic and had a garlic-like sense of taste when consumed. At the time, Saytzeff had no fashion to predict that his discovery was going to prove highly controversial throughout its entire medical history, that it was going to exist tested in thousands of studies and provide miraculous relief for numerous patients.

I'yard talking here about dimethyl sulfoxide (DMSO), an organic sulfur compound which was used only equally an industrial solvent, that is, until its medical properties were discovered in 1963 by a research team headed by Stanley Due west. Jacob, MD.

DMSO is a past-product of kraft pulping (the 'sulfate procedure') which converts wood into wood pulp leaving about pure cellulose fibers. As industrial as it may audio, the process simply entails a treatment of woods chips with a mixture of sodium hydroxide and sodium sulfide, known every bit white liquor, breaking the bonds which link lignin (from the Latin word lignum, meaning wood) to the cellulose.

DMSO is useful as a pain reliever and as well in burns, acne, arthritis, mental retardation, strokes, amyloidosis, head injury, scleroderma, information technology soothes toothaches, eases headaches, hemorroids, muscle strains, information technology prevents paralysis from spinal-chord injuries and softens scar tissues. In fact, it is useful in well over 300 ailments and is safe to use. You might think that a compound that has so many alleged uses and benefits should exist automatically suspect, and so permit'due south have a shut wait at its properties and the data available and we'll shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Bike which distributes bioavailable sulfur for all animal and establish life (Parcell, 2002). Sulfur compounds are found in all body cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they accept potential clinical applications in the handling of a number of conditions such as depression, fibromyalgia, arthritis, interstitial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the one that has the widest range and greatest number of therapeutic applications ever shown for whatsoever other single chemic. It has effectually 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to use some DMSO after hearing of its capabilities. The headache was gone in minutes, came dorsum in four hours, and left for good after DMSO was applied a second time. Used for ane purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman'southward sinusitis. A woman who had had a stroke found after DMSO was painted on her painful jaw that she could now write with her paralyzed hand and could walk ameliorate. (Haley, 2000)

Therapeutic Properties

DMSO is an constructive hurting killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating claret vessels and increasing delivery of oxygen and past reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. Information technology is among the most potent free radical scavengers known to man, if non the virtually potent one. This is a crucial mechanism since some molecules in our bodies produce an diff number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are so expelled from the body with the DMSO.

Dr Stanley Jacob working with DMSO in the 1960s

DMSO besides penetrates the pare and the blood-brain barrier with ease, penetrating tissues, and inbound the bloodstream. Furthermore, DMSO protects the cells from mechanical harm and less of it is needed to achieve results every bit time passes equally oppossed to most pharmaceuticals where increasing doses are required. Information technology has a calming effect in the central nervous system and it reaches all areas of the body, when absorbed through the skin, including the encephalon. That is, DMSO applied to i area often leads to pain relief in some other location due to its systemic effect.

It acts as a carrier for other substances or drugs and it also potentiates their effect. In fact, certain drugs dissolved in DMSO, such equally corticoids, antibiotics and insulin, may exist used in a lower dose than usual without reducing their therapeutic efficacy and in add-on, their undesirable side effects are greatly diminished. Also, drugs are able to pass through the blood-brain barrier which is usually bulletproof.

DMSO promotes the excretion of urine and functions as a musculus relaxant. It boosts the immune system, increasing the production of white cells and macrophages that destroy foreign material and pathogens in the torso. It also has anti-bacterial, anti-viral and anti-fungal properties. DMSO also increases the permeability of cell membranes, allowing a flushing of toxins from the prison cell.

DMSO has radioprotective properties against lethal and mutagenic effects of X-rays in cells, cellular systems and whole animals. It likewise has cryoprotective properties, meaning that information technology is capable of protecting against injury due to freezing.
DMSO has likewise been shown to have cholinesterase properties (Sams, 1967), in other words, it inhibits an enzyme from breaking downwardly acetylcholine, increasing both the level and elapsing of action of this important neurotransmitter. Acetylcholine is responsible for learning and retentivity and is also calming and relaxing. Acetylcholine is also a major factor in regulating the immune system, acting as a major brake on inflammation in the body.

Every bit a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, pb, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Large Pharma Obstacles

DMSO is sold in wellness food stores, mail-gild outlets, on the Internet, and in most countries effectually the world. It is used past millions for its wellness benefits yet in the U.S., DMSO has FDA approval only as a preservative of stem cells, bone marrow cells, and organs for transplant, and for interstitial cystitis - a painful inflammatory condition of the bladder which is very difficult to treat with other therapies.

That DMSO has not found favor as a remedy for other medical conditions is partly due to the inability to examination information technology in double-blind experiments. Blind studies, as the proper noun suggests, requires that a report be done without knowing which patient is taking the placebo or the drug. In the case of the DMSO, a bullheaded study is impossible since the peculiar garlic-like gustatory modality and odor (no matter the route of awarding) gives it away and no satisfactory placebo could be devised that would mimic this particular effect of DMSO (Steinberg, 1967).

The FDA and 'big pharma' would prefer we remain dependent on their drugs

If you search for DMSO on the U.S. National Library of Medicine (pubmed.gov), you'll get almost thirty,000 indexed results, making information technology 1 of the almost studied compounds of our time. Yet, nosotros are led to believe that DMSO can't pass the required regulations for its approval in other medical atmospheric condition even though its effectiveness and low toxicity profile is unquestionable.

You run into, DMSO is a mutual chemical that can be manufactured cheaply. No drug visitor can go an exclusive patent since it is also a natural chemical compound, therefore there is no significant financial return. In fact, an executive of a major drug company is quoted equally saying, "I don't care if DMSO is the major drug of our century and nosotros all know it is, it isn't worth information technology to the states" [CBS TV show lx minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, it would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Agency of Drugs of the FDA, J. Richard Crout, M.D., "DMSO is a low toxicity and safe compound (...) I recall that information technology is a fact of life that drug companies are not going to invest in something unless they think in that location is some fiscal return" [CBS TV show threescore minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the use of DMSO, thousands of Americans buy it on the 'black market place' each year, its popularity due not to publicity, only rather 'give-and-take of mouth'. When yous have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family!

In Perspective

In the 1960s, enquiry with DMSO on humans was temporarily halted after certain animals treated with DMSO were institute to accept changes in the middle lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), merely nevertheless, enquiry was gradually restarted after no show was establish of eye changes in humans. As Daniel Haley reports in his volume Politics in Healing: "Tests in rabbits, dogs, and pigs (but not humans) had shown some problems. When quantities of DMSO equal to about ten times the maximum human dose were given every day over a period of six months, slight changes in the lenses of the animals' optics would result, enough to produce a slight nearsightedness. The lens changes were not enough to cause dogs difficulty when running - they didn't bump into things - and in some cases, the changes disappeared subsequently the massive DMSO doses were stopped. In no test at that fourth dimension or since has DMSO ever caused cataracts, either in animals or in humans" (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal affliction, both diseases of the eye. This effectiveness was showtime discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for sure musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

Every bit far as optics are concerned, the testify on DMSO is quite to the contrary. When several patients treated with DMSO for muscular problems reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Hill, ophthalmologist at the Academy of Oregon Medical School. Confirming the favorable changes, Dr. Hill began his own experiments with DMSO (after it was known that the lens changes did not happen in humans). His inquiry showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In dissimilarity, the number of medication-related deaths in the U.South. is estimated at over 200,000 a twelvemonth, making medications the third or fourth leading cause of decease (Pezzalla, 2005). Even common pain relievers called NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, account for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every year (Tamblyn et al, 1997). Taking this into consideration, it is safe to declare that DMSO is amid the safest substances in the world today. In fact, the classic exam for toxicity -the LD-fifty test - measures the lethal dose (LD) at which half of a group of examination animals is killed. The LD-50 tests for aspirin and DMSO show that aspirin is 7 times more toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is mostly applied to the pare in a gel, cream, or liquid. It tin be taken by oral cavity or as an intravenous injection, in many cases forth with other drugs. It has as well been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the eye, on the mucous membranes, and into the urinary float. Strenghs and dosages vary widely.

If you are just dealing with pain or an injury, utilise a topical application. Don't drink it. Drinking information technology is for serious detoxing and other internal necessities. If you use a rose scented DMSO foam, chances are that nobody will be able to odor DMSO's garlic-like smell.

The usual oral dose of DMSO is one teaspoon per day of DMSO seventy% (Morton, 1993). But since information technology can trigger detoxification reactions and DMSO'south total excretion from the body tin take several days, it is best to do it simply once a week. Start with one-half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO seventy% only if whatever possible detoxification reaction is well tolerated.

When y'all use liquid DMSO in the skin, allow it dry for over 20 to 30 minutes before wiping the rest out. The pare must be clean, dry, and unbroken for any topical use of DMSO. The confront and the neck are more sensitive to DMSO and no higher concenrations than 50% should be applied there. Topical concentrations of DMSO should be kept below lxx% in areas where there is a reduction of circulation. When 60 to ninety% DMSO is applied to the pare, warmth, redness, itching, and somtimes local hives may occur. This normally disappears within a couple of hours and using natural aloe vera, gel or foam, will assistance counteract or prevent this effect. When 60 to ninety% DMSO is practical to the palm on the hand, the pare may wrinkle and stay that way for several days.

"My brother put some DMSO gel (lxx% dmso, xxx% aloe vera) on his shoulders and lower role of cervix because he had muscle pain/soreness in that area, and it caused peel redness/irritation for a few hours, although it did diminish the muscle soreness too...my grandma has rheumatoid arthritis that made her legs swell up and hurt continuously, and I had her apply the same DMSO gel, and subsequently about 2-3 days of applying it once a day, the swelling was 90% gone, and I think within 4-5 days it was 100% gone, and she said the hurting diminished too." - Michael Shatskiy, Los Angeles, California, United States

Chronic pain patients oftentimes take to apply the substance for half-dozen weeks before a change occurs, simply many report relief to a degree that had not been able to obtain from any other source. In general, the greater the chronicity of the disorder, the longer the treatment with DMSO must be employed in order to attain palliation (Steinberg , 1967).

Common health issues for which people will use topical DMSO at home include acute musculoskeletal injuries and inflammations. The before DMSO is used, the more dramatic the event. A 70% concentration of DMSO mixed with h2o in volumes ranging from eight to 12 ml, applied on and around the injury in a wide area at least three times daily, will accept a healing affect in iv out ot 5 people.

Arthritis, Sprains, Strains

Information technology provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. You can see a positive response within 5 to 20 minutes and normally lasting for four to 6 hours. (Steinberg, 1967).

"Applying DMSO where information technology hurt to a half dozen-year-quondam wasted from rheumatoid arthritis, in a half hour the child could motion her shoulder and turn her caput for the first time in two years. Persuaded to try walking, she managed a few steps and so burst into tears. "Why are you lot crying?" Dr Jacob asked her. "Because information technology doesn't hurt anymore", she replied. (Haley, 2000)

"My brother has arthritis of the spine. He is in pain and bedridden more than half the time. When he is treated with DMSO, he is able to lead a normal, active life... Just 1 awarding of this inexpensive, prophylactic DMSO inverse my brother from a grimacing patient into an active, pain-free man in exactly thirty minutes!" (Haley, 2000)

June Jones, once quarterback and later bus of the Atlanta Falcons pro-football team, had a bursitis calcification in his right shoulder. His career almost didn't happen equally he could hardly lift his arm, let lone throw a football. But he was aware of DMSO and had used DMSO for sprains, similar thousands of others. He received a shot of DMSO in the shoulder and afterward using DMSO for 30 days directly, the calcification disappeared. (Haley, 2000)

Stroke

Given soon after a stroke, DMSO can dissolve the jell that causes the stroke, restoring apportionment and fugitive paralysis. Once DMSO gets into the body either daubed on the skin, given in I.Five., or by mouth, it permeates the trunk and crosses the brain barrier, so even taken orally it tin ameliorate apportionment. Ideally information technology should exist I.5.

Even though DMSO 40% causes a prolongation of bleeding fourth dimension, it is withal indicated for use in treating embolic or hemorrhagic stroke. DMSO is superior to any other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

1 man who had a stroke at vii:30 AM refused to go to the hospital until later on his married woman had spoken with Dr. Stanley Jacob, which didn't happen until half-dozen:xxx PM. Starting at 7 PM the solar day of the stroke, she gave him ane ounce of 50% DMSO in a little orange juice every 15 minutes for two hours and and so every half hour for two hours. The next 24-hour interval, her husband was better and shortly returned to normal. A substance that can terminate a stroke equally information technology's happening is something many might want in their home medicine chest .(Haley, 2000)

Angina, Heart Attacks, Injuries of the Brain and Spinal Chord

DMSO may help neutralize harmful effects on the heart and brain in medical disorders involving the head and spinal chord injury, stroke, retentivity dysfunction, and ischemic heart illness (Jacob, de la Torre, 2009). A 40% DMSO solution should exist administered within 4 hours to be effective, within ninety minutes is best.

After I.V. assistants of DMSO, there is an acme in the amount of spinal cord blood catamenia to the region of trauma. One of the first things that happens after spinal string trauma is that a reduction of oxygen and claret menses sets in, inasmuch as the claret vessels constrict or shut down... Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the fauna will either become comatose or lethargic or die. With DMSO infusion immediately later injury (or stroke) all this is prevented. - Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico

Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed - paraplegics - and some regained use of limbs. Ane man, quadraplegic, recovered plenty to go through college and and so to work in a banking company. (Haley, 2000)

Infections

When combined with antibiotics, DMSO volition convert bacteria which are resistant to a given antibody to being sensitive to that aforementioned antibiotic and probably a fourscore to 90 per cent solution of DMSO volition be required in society to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to transport antibiotics to difficult-to-reach areas of the trunk with splendid results, such as the os marrow and brain (Sanders, 1967).

DMSO tin can dissolve a virus protein blanket, leaving the virus cadre unprotected with its nucleic acid exposed to the immune organisation. Applied topically, information technology alleviates the lesions that occur as a effect of Canker Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the confront, DMSO can open blocked sinuses inside a few minutes and it has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear up gum illness and reduce tooth disuse and their hurting by painting it on the involved areas.

"I have some pharmaceutical grade DMSO and I pour well-nigh two teaspoons in a glass in the evening, put my 20 mg of doxycycline in it, add together about ii teaspoons of distilled water, and then swish it around in my mouth for most ii or 3 minutes and so swallow it. And so I approximate information technology is about 50% solution. It'south actually working on my rima oris. That inflamed area of my jaw has calmed down about 70% in simply a couple of days. Or more than, actually. I wait it to be completely soothed past tomorrow after tonight'southward dose of DMSO." - L., Toulouse, France

Several books accept been published on the benefits of DMSO

Keloids, Scars, Burns, Bruises

A concentration of 50 to fourscore% put on two or three times a day volition flatten a raised scar after several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied rapidly to an injury, it can eliminate whatsoever bruising.

"I take been applying it to my face up for two weeks... I had a bout of acne in March, and this healed the damage pretty well but what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it's astonishing!" - HG, Us

"I diluted a l% solution and practical it topically to the inflamed lymph node. I applied it again this evening. I am totally amazed! There is a noticeable decrease in the size of the node, in just two applications! And it no longer feels matted. This node has been bloated for over 20 years!!! - Melissa Medlock, Coldwater, Michigan, USA

Podiatry

DMSO can be effective in the treatment of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.
Varicose veins and thrombophlebitis

Topical DMSO can whiten telangiectasias, small dilated claret vessels near the surface of the skin. Information technology can besides decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye issues

I drop of a 25% DMSO solution (diluted in sterile physiologic or saline solution) once or twice per mean solar day is useful for heart problems, including cataracts or glaucoma.

"DMSO is astonishing, I've besides read various good results with using it in the eyes. Beingness the audacious type myself, today I diluted DMSO down to 30% and put 2 drops in 1 of my optics that has been having cerise spots around the iris. The red spots diminished drastically. The only side effect was a slight called-for sensation, similar to those drops you get when one goes for a glaucoma test, without the side event of dilated pupils." - DZ, U.s.

Headaches

DMSO is highly effective in vascular headaches and in muscular tension which so oftentimes goes with headaches. It may exist used on hairy areas such as the scalp and it likewise may exist used near the eyes. A ninety% solution is more constructive (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the post-obit diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (ii) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal beliefs or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attention to an extraordinary paper presented by Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia University in Lima, Peru. After extensive tests on animals and then on normal humans, Dr. Ramirez reported "injecting fifty% or 80% DMSO intramuscularly into patients with acute and chronic schizophrenia" and that "of the 14 acute cases, every unmarried i was discharged from the hospital inside 45 days afterward the start of DMSO treatment... He said that 4 of the xi chronic cases, one of whom has been ill for fourteen years, were discharged eventually, and the other 7 improved a great deal and were given occupational therapy... He observed rapid subtract in agitation... recession of persecution feeling, a relatively sudden tendency to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and anxiety". (Haley, 2000)

Genitourinary disorders

DMSO has been used in the handling of a number of patients with various genitourinary disorders, including Peyronie's disease, interstitial cystitis, acute epididymitis. Some have obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).

Miscellaneous

DMSO in conjunction with other treatments has shown to regress cancer in a very constructive style (Ayre, 1967).

Intravenous administration of DMSO markedly reduces pathological intestinal permeability while preserving the gut'southward absorption capacities (Wang et al, 1996). Considering that gut permeability ('leaky gut') has a key office in chronic degenerative diseases, this is of great clinical importance.

DMSO also has fantabulous results in the skin of people afflicted with scleroderma, results which take never been observed with whatever other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy'south sub-committee on health in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would help, and that she would probably soon face a wheelchair and early death. By the fourth dimension she constitute Dr. Jacob (through give-and-take of rima oris), she told the Senators, "I was having difficulty breathing, walking, and eating". The disease "thickens the tissue and makes your skin so tight y'all cannot motion. Information technology was difficult for me to drive, to turn the ignition in my automobile or turn my body". Her dentist could not work on her for awhile because she could not open her mouth. "At present I can open my mouth like anybody", she said. Afterward her sensitized skin burned from topical application of DMSO, Dr. Jacob suggested taking it orally. "Within six months", she testified, "my condition reversed almost immediately. I can practice anything everyone else can do now" (Haley, 2000).

Hopefully, this brief overview of DMSO's peachy capabilities has helped to illustrate how information technology is indeed, the cure of our times. I'g convinced of its therapeutic power, both by my own experience and that ane of scores of people, not to mention the redundancy of published scientific literature. Its uses and applications brand it a very handy compound to have on your medical shelf. In pure form, the life of DMSO is indefinite, so information technology may be used for years.

Troubleshooting

The garlic-like torso scent and taste in the rima oris that some experience is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This can last for one or 2 days and in a small-scale number of people, especially men, the scent tin exist very pungent. Drinking enough water will help diffuse the smell. Other side effects - such as stomach upset, headaches, dizziness, and sedation - are very likely related to detoxification reactions prompted by the DMSO.

Only purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, e'er do information technology in distilled water. When it is practical, the peel site also as the applying paw should be thoroughly cleaned earlier application. This is of utmost importance as DMSO's properties allow contaminants to be absorbed through the skin and transported into the bloodstream.

DMSO is known to exist i of the least toxic substances in biology (Parcell, 2002), then whatever serious side effects should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and any substance dissolved in information technology, will penetrate the skin, the blood-brain bulwark, and other parts of the body very fast.

Remember also that DMSO increases the effects of drugs similar blood thinners, steroids, heart medicines, sedatives, etc. In addition to that, acetone or acid contagion of DMSO can lead to serious medical consequences. Exist aware of this problem when ownership unreliable DMSO. A pure DMSO solution will plow solid (like water ice) in the refigerator within 2 hours. If, when the frozen canteen is turned upside down, little rivulets of water period through the ice, you probably possess the veterinary grade DMSO. This is a xc% concentration. Ten percentage is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen homo embryos. DMSO tin interfere with liver function tests and give a simulated reading. That problem is easily solved by waiting a week afterwards DMSO usage before taking the test.

Long-term use has been documented every bit safe. Middle impairment, reported in laboratory animals, has non been confirmed. Side effects such equally skin rash and itching after topical application, breaking up of blood elements later on intravenous infusion, tin can be avoided in large part by employing more than dilute solutions. Despite these side effects, DMSO is used as a preservative for blood elements and stalk cells (McKim, Strub, 2008).

When DMSO is diluted with water, heat is released. The bottle will be warm to the bear on. This is a temporary, harmless reaction.

Since DMSO causes dryness and scaling of the outer layer of the peel, skin diseases characterized by scaling (psoriasis) could be aggravated past the employ of DMSO. Simply DMSO applied topically for only a few days has been useful in psoriasis. Prolonged use of DMSO for the treatment of psoriasis is non advised however, as it tin worsen the psoriatic status (Engel, 1967), only DMSO taken orally is suggested.

"I'm happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to take care of many of my remaining psoriasis bug. A couple areas are still being stubborn, only I've noticed a lot of general improvement. Using DMSO topically besides helped amend a patch of eczema that my wife has been bothered past for quite a while." - Peter Norquest, Tucson, Arizona, Us

DMSO2, a derivative of DMSO, is better tolerated and doesn't take the odour and irritation side effects. Despite this positive aspect, it hasn't surpassed the effectiveness, fascination and popularity of DMSO. It is also known equally methylsufonlmethane or MSM, an entire topic for some other article by itself!

Sulfur is an chemical element of the earth and it is essential to life, information technology as among the most prevalent elemenents in the man trunk. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are 'allergic to sulfur', what they really mean is that they are allergic or sensitive mainly to certain sulfur-containing drugs or proteins, virtually notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a high sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or loftier sulfur containing foods (similar the author) exercise not experience bug taking DMSO, because apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with caution, do your homework, and consult a wellness care provider in case of doubts.

References:

Ayre JE, LeGuerrier J. Some (regressive) furnishings of DMSO dexamethasone upon cervical cells in cervical dysplasia and carcinoma in situ. Ann N Y Acad Sci. 1967 Mar xv;141(1):414-22.

Blumenthal LS, Fuchs M. The clinical use of dimethyl sulfoxide on various headaches, musculoskeletal, and other general medical disorders. Ann North Y Acad Sci. 1967 Mar xv;141(1):572-85.

Engel MF. Indications and contraindications for the use of DMSO in clinical dermatology. Ann Northward Y Acad Sci. 1967 Mar xv;141(i):638-45.

Goldman J. A cursory resume of clinical observations in the treatment of superficial burns, trigeminal neuralgia, acute bursitis, and acute musculo-skeletal trauma with dimethyl sulfoxide. Ann N Y Acad Sci. 1967 Mar 15;141(ane):653-4.

Gordon DM. Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects. Ann N Y Acad Sci. 1967 Mar 15;141(one):392-401.

Haley Daniel. Politics in Healing. Potomac Valley Press, 2000.

Jacob SW, de la Torre JC. Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. Pharmacol Rep. 2009 Mar-April;61(2):225-35.

Marvin P. Interval therapy with Dimethyl Sulfoxide. Annals of the New York Academy of Sciences. Volume 141, Biological Actions of Dimethyl Sulfoxide pages 551 - 554.

McKim A.Southward., Strub Robert. Dimethyl Sulfoxide USP, PhEur in Approved Pharmaceutical Products and Medical Devices. Pharmaceutical Technology, May 2008.

Ogden HD. Experiences with DMSO in treatment of headache. Ann Due north Y Acad Sci. 1967 Mar 15;141(one):646-8.

Parcell S. Sulfur in human being nutrition and applications in medicine. Altern Med Rev. 2002 Feb;vii(1):22-44.

Persky L, Steeart BH. The use of dimethyl sulfoxide in the treatment of genitourinary disorders. Ann N Y Acad Sci. 1967 Mar 15;141(ane):551-4.

Pezalla E. Preventing adverse drug reactions in the full general population. Manag Care Interface. 2005 Oct;18(ten):49-52.

Pottz GE, Rampey JH, Benjamin F.Ann- The event of dimethyl sulfoxide (DMSO) on antibiotic sensitivity of a group of medically of import microorganisms: preliminary report. Ann N Y Acad Sci. 1967 Mar 15;141(1):261-72.

Ramírez E, Luza S. Dimethyl sulfoxide in the handling of mental patients. Ann N Y Acad Sci. 1967 Mar xv;141(1):655-67.

Sams WM Jr. The effects of dimethyl sulfoxide on nerve conduction. Ann N Y Acad Sci. 1967 Mar fifteen;141(1):242-vii.

Sanders M. Discussion. Register of the New York Academy of Sciences. Book 141, Biological Actions of Dimethyl Sulfoxide pages 649 - 652, March 1967.

Scherbel AL, McCormack LJ, Layle JK. Further observations on the effect of dimethyl sulfoxide in patients with generalized scleroderma. (Progressive systemic sclerosis). Ann Northward Y Acad Sci. 1967 Mar 15;141(1):613-29.

Steinberg A. The employment of dimethyl sulfoxide equally an antiinflammatory agent and steroid-transporter in diversified clinical diseases. Ann N Y Acad Sci. 1967 Mar xv;141(1):532-50.

Tamblyn R, Berkson L, Dauphinee WD, Gayton D, Grad R, Huang A, Isaac L, McLeod P, Snell L. Unnecessary prescribing of NSAIDs and the management of NSAID-related gastropathy in medical practice. Ann Intern Med. 1997 Sep fifteen;127(6):429-38.

Walker Morton. DMSO Nature's Healer. New York: Avery, 1993.

Wang XD, Wang Q, Andersson R, Ihse I. Alterations in abdominal office in acute pancreatitis in an experimental model. Br J Surg. 1996 November;83(eleven):1537-43.

Near the author:
Gabriela Segura M.D. is a centre surgeon with extensive feel and involvement in alternative wellness reasearch, psychology and the human status. She is a regular contributor to Sott.net and maintains her health website Health Matrix

romanhathimerent38.blogspot.com

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